Article
Obesity-related loci in TMEM18, CDKAL1 and FAIM2 are associated with obesity and type 2 diabetes in Chinese Han patients.
BMC medical genetics - 30 Mar 2020
Kang Jing, Guan Ren-Chu, Zhao Ying, Chen Yan
Abstract excerpt
BACKGROUND: Several obesity susceptibility loci in genes, including GNPDA2, SH2B1, TMEM18, MTCH2, CDKAL1, FAIM2, and MC4R, have been identified by genome-wide association studies. The purpose of this study was to investigate whether these loci are associated with the concurrence of obesity and type 2 diabetes in Chinese Han patients. METHODS: Using the SNaPshot technique, we genotyped seven single nucleotide...
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