Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Congenital fibrinogen disorder caused by digenic mutations of the FGA and FGB genes.

Hematology (Amsterdam, Netherlands) - 1 Dec 2020

Wang Xiong, Tang Ning, Shen Na, Lu Yanjun, Li Dengju

Abstract excerpt

Objectives: Congenital fibrinogen disorders (CFDs) are caused by monoallelic or biallelic mutations in FGA, FGB, and FGG genes. Quantitative CFDs include afibrinogenemia and hypofibrinogenemia, while qualitative CFDs consist of dysfibrinogenemia and hypodysfibrinogenemia. Hypofibrinogenemia and dysfibrinogenemia are autosomal dominant disorders while afibrinogenemia is a recessive one. We aimed to perform genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Afibrinogenemia
Share to Fibrinogen
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32228225
DOI: 10.1080/16078454.2020.1746109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Congenital fibrinogen disorder caused by digenic mutations of the FGA and FGB genes.PMID 32228225Read ↗

Genetic mutations associated with congenital fibrinogen disorders: global distribution and clinical outcomes.Semantic proximity Read ↗

Clinical and molecular characterization of Iranian patients with congenital fibrinogen disorders.Semantic proximity Read ↗

Molecular and clinical profile of congenital fibrinogen disorders in Iran, identification of two novel mutations.Semantic proximity Read ↗

Congenital Fibrinogen Deficiencies: Not So RareSemantic proximity Read ↗

Congenital dysfibrinogenemia caused by a heterozygous mutation in the FGA gene: A case report and review of literatureSemantic proximity Read ↗

Mutations in inherited fibrinogen disorders correlated with clinical features in the Chinese population.Semantic proximity Read ↗

A novel mutation in the FGG gene causes hypofibrinogenemia in a Chinese family.Semantic proximity Read ↗

Mutations Accounting for Congenital Fibrinogen Disorders: An Update.Semantic proximity Read ↗

[Clinical phenotypes and genotypes of congenital fibrinogen disorder: an analysis of 16 children].Semantic proximity Read ↗

Identification of a novel mutation in congenital afibrinogenemia in Iranian patients.Semantic proximity Read ↗

Genetic Variants in the FGB and FGG Genes Mapping in the Beta and Gamma Nodules of the Fibrinogen Molecule in Congenital Quantitative Fibrinogen Disorders Associated with a Thrombotic Phenotype.Semantic proximity Read ↗

A novel missense mutation (FGG c.1168G > T) in the gamma chain of fibrinogen causing congenital hypodysfibrinogenemia with bleeding phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.