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Flotillin: A Promising Biomarker for Alzheimer’s Disease

26 Mar 2020

Abstract excerpt

Alzheimer’s disease (AD) is characterized by the accumulation of beta amyloid (Aβ) in extracellular senile plaques and intracellular neurofibrillary tangles (NFTs) mainly consisting of tau protein. Although the exact etiology of the disease remains elusive, accumulating evidence highlights the key role of lipid rafts, as well as the endocytic pathways in amyloidogenic amyloid precursor protein (APP) processing...

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PMID: 32225073
DOI: 10.3390/jpm10020020

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