Article
Implications of HLA diversity among regions for bone marrow donor searches in Japan.
HLA - 1 Jul 2020
Hashimoto Shiho, Nakajima Fumiaki, Imanishi Tadashi, Kawai Yosuke, Kato Kazue, Kimura Takafumi, Miyata Shigeki, Takanashi Minoko, Nishio Miwako, Tokunaga Katsushi, Satake Masahiro
Abstract excerpt
Japan is an island country, and the Japanese people have had minimal genetic exchange with other ethnolinguistic groups. Consequently, the population is highly uniform and has limited HLA diversity relative to people from other countries. However, Japan has three ethnolinguistic groups, and HLA distributions differ depending on geographic region. To collect an HLA-rich variety of bone marrow bank donor...
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