Article
Influence of Cytochrome P450 2D6 Polymorphisms on the Efficacy of Oral Propranolol in Treating Infantile Hemangioma.
BioMed research international - 1 Jan 2020
Wang Lidan, Zheng Kai, Li Xinlin, Wang Yang, Xu Qiong
Abstract excerpt
OBJECTIVE: The aim of this study is to evaluate the association of genetic polymorphisms in Cytochrome P450 2D6(CYP2D6) and the change in VEGF levels with the response to propranolol in patients with Infantile hemangiomas (IH). METHODS: IH patients who underwent over six months of propranolol therapy and received oral propranolol only were enrolled. The target dose of propranolol was 1 mg kg-1day-1....
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