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Computational models to explore the complexity of the epithelial to mesenchymal transition in cancer

24 Mar 2020

Abstract excerpt

Epithelial to mesenchymal transition (EMT) is a complex biological process that plays a key role in cancer progression and metastasis formation. Its activation results in epithelial cells losing adhesion and polarity and becoming capable of migrating from their site of origin. At this step the disease is generally considered incurable. As EMT execution involves several individual molecular components, connected...

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PMID: 32208556
DOI: 10.1002/wsbm.1488

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