Article
A mutant vesicular stomatitis virus with reduced cytotoxicity and enhanced anterograde trans-synaptic efficiency.
Molecular brain - 20 Mar 2020
Lin Kunzhang, Zhong Xin, Ying Min, Li Lei, Tao Sijue, Zhu Xutao, He Xiaobin, Xu Fuqiang
Abstract excerpt
Understanding the connecting structure of brain network is the basis to reveal the principle of the brain function and elucidate the mechanism of brain diseases. Trans-synaptic tracing with neurotropic viruses has become one of the most effective technologies to dissect the neural circuits. Although the retrograde trans-synaptic tracing for analyzing the input neural networks with recombinant rabies and...
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