Article
Characteristics of Early Paget's Disease in SQSTM1 Mutation Carriers: Baseline Analysis of the ZiPP Study Cohort.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jul 2020
Cronin Owen, Subedi Deepak, Forsyth Laura, Goodman Kirsteen, Lewis Steff C, Keerie Catriona, Walker Allan, Porteous Mary, Cetnarskyj Roseanne, Ranganath Lakshminarayan R, Selby Peter L, Hampson Geeta, Chandra Rama, Ho Shu, Tobias Jon H, Young-Min Steven A, McKenna Malachi J, Crowley Rachel K, Fraser William D, Tang Jonathan, Gennari Luigi, Nuti Rannuccio, Brandi Maria-Luisa, Del Pino-Montes Javier, Devogelaer Jean-Pierre, Durnez Anne, Isaia Giovanni Carlo, Di Stefano Marco, Rubio Josep Blanch, Guanabens Nuria, Seibel Markus J, Walsh John P, Kotowicz Mark A, Nicholson Geoffrey C, Duncan Emma L, Major Gabor, Horne Anne, Gilchrist Nigel L, Ralston Stuart H
Abstract excerpt
Mutations in SQSTM1 are strongly associated with Paget's disease of bone (PDB), but little is known about the clinical characteristics of those with early disease. Radionuclide bone scans, biochemical markers of bone turnover, and clinical characteristics were analyzed in SQSTM1 mutation carriers who took part in the Zoledronic acid in the Prevention of Paget's disease (ZiPP) study. We studied 222 individuals, of...
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