Article
Cancer vaccines: Targeting KRAS-driven cancers.
Expert review of vaccines - 1 Feb 2020
Zhang Ying, Ma Jin-An, Zhang Hai-Xia, Jiang Yu-Na, Luo Wen-Hao
Abstract excerpt
Introduction: Mutant KRAS is a genetic driver of multiple cancers that has challenged clinical anti-cancer therapeutics in the last 3 decades. Neo-antigens encoded by KRAS mutations have been identified as tumor-specific with high immunogenicity and can be used to deliver precision cancer vaccines to promote anti-tumor immune responses. KRAS mutation-based cancer vaccines have produced encouraging preclinical and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
