Article
The anti-TH17 polarization effect of Indigo naturalis and tryptanthrin by differentially inhibiting cytokine expression.
Journal of ethnopharmacology - 12 Jun 2020
Cheng Hui-Man, Kuo Yi-Zih, Chang Che-Ying, Chang Chun-Han, Fang Wei-Yu, Chang Chen-Ni, Pan Shin-Chen, Lin Jin-Yuarn, Wu Li-Wha
Abstract excerpt
ETHNOPHARMACOLOGICAL RELEVANCE: The Chinese herbal medicine Qing-Dai (also known as Indigo naturalis) extracted from indigo-bearing plants including Baphicacanthus cusia (Ness) Bremek was previously reported to exhibit anti-psoriatic effects in topical treatment. TH17 was later established as a key player in the pathogenesis of psoriasis. We investigated the anti-TH17 effect of Indigo naturalis and its active...
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