Interactions between the MMP-3 gene rs591058 polymorphism and occupational risk factors contribute to the increased risk for lumbar disk herniation: A case-control study.

doi:10.1002/jcla.23273

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Article

Interactions between the MMP-3 gene rs591058 polymorphism and occupational risk factors contribute to the increased risk for lumbar disk herniation: A case-control study.

Journal of clinical laboratory analysis - 1 Jul 2020

Luo Yongjun, Wang Jiaxing, Pei Jie, Rong Yuluo, Liu Wei, Tang Pengyu, Cai Weihua, Yin GuoYong

Abstract excerpt

OBJECTIVE: Lumbar disk herniation (LDH) is a complex condition based on lumbar disk degeneration (LDD). Previous studies have shown that genetic factors are highly associated with the severity and risk for LDH. This case-control study was aimed to evaluate the association between the matrix metalloproteinase (MMP)-3 gene rs591058 C/T polymorphism and LDH risk in a southern Chinese population. METHODS: A total of...

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PMID: 32157746
DOI: 10.1002/jcla.23273
PMCID: PMC7370738

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