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Article

The extracellular thioredoxin Etrx3 is required for macrophage infection in Rhodococcus equi.

Veterinary research - 10 Mar 2020

Mourenza Álvaro, Collado Cristina, Bravo-Santano Natalia, Gil José A, Mateos Luís M, Letek Michal

Abstract excerpt

Rhodococcus equi is an intracellular veterinary pathogen that is becoming resistant to current antibiotherapy. Genes involved in preserving redox homeostasis could be promising targets for the development of novel anti-infectives. Here, we studied the role of an extracellular thioredoxin (Etrx3/REQ_13520) in the resistance to phagocytosis. An etrx3-null mutant strain was unable to survive within macrophages,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32156317
DOI: 10.1186/s13567-020-00763-3
PMCID: PMC7063783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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