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Unbalanced Sphingolipid Metabolism and Its Implications for the Pathogenesis of Psoriasis

3 Mar 2020

Abstract excerpt

Sphingolipids (SLs), which have structural and biological responsibilities in the human epidermis, are importantly involved in the maintenance of the skin barrier and regulate cellular processes, such as the proliferation, differentiation and apoptosis of keratinocytes (KCs). As many dermatologic diseases, including psoriasis (PsO), intricately characterized by perturbations in these cellular processes, are...

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PMID: 32138315
DOI: 10.3390/molecules25051130

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