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Article

Expression of telomerase reverse transcriptase positively correlates with duration of lithium treatment in bipolar disorder.

Psychiatry research - 1 Apr 2020

Lundberg Martin, Biernacka Joanna M, Lavebratt Catharina, Druliner Brooke, Ryu Euijung, Geske Jennifer, Colby Colin, Boardman Lisa, Frye Mark, Schalling Martin

Abstract excerpt

Bipolar disorder (BD) may be associated with accelerated cellular aging. However, previous studies on telomere length (TL), an important biomarker of cellular aging, have yielded mixed results in BD. We aimed to evaluate the hypothesis that BD is associated with telomere shortening and whether this is counteracted by long-term lithium treatment. We also sought to determine whether long-term lithium treatment is...

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Identifiers

PMID: 32114208
DOI: 10.1016/j.psychres.2020.112865
PMCID: PMC7334059

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