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Inducing human induced pluripotent stem cell differentiation through embryoid bodies: A practical and stable approach

26 Dec 2019

Abstract excerpt

simulation, and organoid establishment. EBs can potentially also be used in early prediction of iPSC differentiation capability. To improve the stability and feasibility of EB-mediated differentiation and generate high quality EBs, critical factors including iPSC pluripotency maintenance, generation of uniform morphology using micro-pattern 3D culture systems, proper cellular density inoculation, and EB size...

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PMID: 32110273
DOI: 10.4252/wjsc.v12.i1.25

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