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Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker

27 Feb 2020

Abstract excerpt

To define cellular mechanisms underlying kidney function and failure, the KPMP analyzes biopsy tissue in a multicenter research network to build cell-level process maps of the kidney. This study aimed to establish a single cell RNA sequencing strategy to use cell-level transcriptional profiles from kidney biopsies in KPMP to define molecular subtypes in glomerular diseases. Using multiple sources of adult human...

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Chronic Kidney Disease and Diabetes
Renal Diseases and Glomerulopathies
Single-cell and spatial transcriptomics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 32107344
DOI: 10.1172/jci.insight.133267

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