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Long Noncoding RNA NRAV Promotes Respiratory Syncytial Virus Replication by Targeting the MicroRNA miR-509-3p/Rab5c Axis To Regulate Vesicle Transportation

26 Feb 2020

Abstract excerpt

The mechanism of interaction between RSV and host noncoding RNAs is not fully understood. In this study, we found that the expression of long noncoding RNA (lncRNA) negative regulator of antiviral response (NRAV) was reduced in RSV-infected patients, and overexpression of NRAV facilitated RSV production in vitro , suggesting that the reduction of NRAV in RSV infection was part of the host antiviral response. We...

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PMID: 32102886
DOI: 10.1128/jvi.00113-20

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