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Article

ViroPanel: Hybrid Capture and Massively Parallel Sequencing for Simultaneous Detection and Profiling of Oncogenic Virus Infection and Tumor Genome.

The Journal of molecular diagnostics : JMD - 1 Apr 2020

Slevin Michael K, Wollison Bruce M, Powers Winslow, Burns Robert T, Patel Neil, Ducar Matthew D, Starrett Gabriel J, Garcia Elizabeth P, Manning Danielle K, Cheng Jingwei, Hanna Glenn J, Kaye Kenneth M, Van Hummelen Paul, Nag Anwesha, Thorner Aaron R, DeCaprio James A, MacConaill Laura E

Abstract excerpt

Precision cancer medicine aims to classify tumors by site, histology, and molecular testing to determine an individualized profile of cancer alterations. Viruses are a major contributor to oncogenesis, causing 12% to 20% of all human cancers. Several viruses are causal of specific types of cancer, promoting dysregulation of signaling pathways and resulting in carcinogenesis. In addition, integration of viral DNA...

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Cell Transformation, Viral
Computational Biology
Genome, Human
Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Precision Medicine

Sensitivity and Specificity

Tumor Virus Infections

Virus Integration

Source

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Identifiers

PMID: 32068070
DOI: 10.1016/j.jmoldx.2019.12.010
PMCID: PMC7193840

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