Article
Discovery of candidate gene expression signatures in peripheral blood for the screening of cervical cancer.
Biomarkers in medicine - 1 Feb 2020
Ma Qiuling, Shao Yong, Chen Wei, Quan Cheng, Zhu Yanhui, Xu Xiaohong, Zhou Zhe, Wang Shengqi
Abstract excerpt
Aim: To investigate whether cervical cancer (CC) and cervical intraepithelial neoplasia (CIN) can be screened by analyzing gene expression profiling of peripheral blood. Methods: RNA-sequencing analysis of blood was performed on 11 CC patients, 21 CIN patients and 19 healthy controls (H). Fifty-nine genes were validated by quantitative real-time PCR using blood samples from 46 H, 83 CC and 32 CIN patients....
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