Article
Beta cell function and insulin sensitivity in obese youth with maturity onset diabetes of youth mutations vs type 2 diabetes in TODAY: Longitudinal observations and glycemic failure.
Pediatric diabetes - 1 Jun 2020
Arslanian Silva, El Ghormli Laure, Haymond Morey H, Chan Christine L, Chernausek Steven D, Gandica Rachelle G, Gubitosi-Klug Rose, Levitsky Lynne L, Siska Maggie, Willi Steven M
Abstract excerpt
OBJECTIVE: In treatment options for type 2 diabetes in adolescents and youth (TODAY), 4.5% of obese youth clinically diagnosed with type 2 diabetes (T2D) had genetic variants consistent with maturity onset diabetes of youth (MODY) diagnosis. The course of IS and β-cell function in obese youth with MODY remains unknown. In this secondary analysis, we examined IS and β-cell function in MODY vs. non-MODY obese youth...
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