Article
Complementation of the Mycoplasma synoviae MS-H vaccine strain with wild-type oppF1 influences its growth characteristics.
Avian pathology : journal of the W.V.P.A - 1 Jun 2020
Kordafshari Somayeh, Marenda Marc S, Agnew Rebecca, Shil Pollob, Shahid Muhammad A, Marth Christina, Konsak Barbara M, Noormohammadi Amir H
Abstract excerpt
The Mycoplasma synoviae (MS) vaccine strain MS-H harbours a frameshift mutation in oppF1 (oligopeptide permease transporter) which results in expression of a truncated OppF1. The effect of this mutation on growth and attenuation of the MS-H is unknown. In this study, the impact of the mutation on the vaccine phenotype was investigated in vitro by introducing a wild-type copy of oppF1 gene in the MS-H genome....
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