Article
Developmental variability channels mouse molar evolution.
eLife - 12 Feb 2020
Hayden Luke, Lochovska Katerina, Sémon Marie, Renaud Sabrina, Delignette-Muller Marie-Laure, Vilcot Maurine, Peterkova Renata, Hovorakova Maria, Pantalacci Sophie
Abstract excerpt
Do developmental systems preferentially produce certain types of variation that orient phenotypic evolution along preferred directions? At different scales, from the intra-population to the interspecific, the murine first upper molar shows repeated anterior elongation. Using a novel quantitative approach to compare the development of two mouse strains with short or long molars, we identified temporal, spatial and...
Topics
- Animals
- Biological Evolution
- Biological Variation, Population
- Embryo, Mammalian
- Female
- Male
- Mice
- Molar
- Phenotype
- Pregnancy
- Signal Transduction
- Tooth Eruption