Article
LncRNA XLOC_003810 modulates thymic Th17/Treg balance in myasthenia gravis with thymoma.
Clinical and experimental pharmacology & physiology - 1 Jun 2020
Niu Li, Jiang Jun, Yin Ying, Hu Bo
Abstract excerpt
Imbalance of T helper 17 (Th17)/regulatory T (Treg) cells is involved in the pathogenesis of myasthenia gravis with thymoma (MG-T). Long non-coding RNAs (lncRNAs) are implicated in the regulation of Th17/Treg balance. This study was designed to explore the role of XLOC_003810, a novel lncRNA, in regulating the Th17/Treg balance in MG-T. The thymic CD4+ T cells were isolated from control subjects and MG-T...
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