Imerslund-Gräsbeck Syndrome presenting with microangiopathic hemolytic anemia in a child.

Abstract excerpt

Imerslund-Gräsbeck Syndrome is a rare autosomal recessive disorder characterized by proteinuria and selective malabsorption of cobalamin. Deficiency of cobalamin can lead to megaloblastic anemia, pancytopenia and even "pseudo"-thrombotic microangiopathy (TMA). Signs of mechanical hemolysis on peripheral blood smear, elevated lactate dehydrogenase and thrombocytopenia are common findings of TMA. We report a child...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Anemia, Hemolytic
• Share to Anemia, Megaloblastic
• Share to Homozygote