Article
BRCA and Beyond: Comprehensive Image-rich Review of Hereditary Breast and Gynecologic Cancer Syndromes.
Radiographics : a review publication of the Radiological Society of North America, Inc - 1 Jan 2000
Chung Stephanie Histed, Woldenberg Nina, Roth Antoinette R, Masamed Rinat, Conlon Wendy, Cohen Joshua G, Joines Melissa M, Patel Maitraya K
Abstract excerpt
In addition to the well-characterized BRCA1 and BRCA2 hereditary breast and ovarian cancer syndromes, many other syndromes that are associated with genetic mutations predispose individuals to an increased risk of breast and gynecologic malignancies. Many mutated genes encode for tumor-suppressor products and are inherited in an autosomal dominant manner. Mutations markedly increase an individual's lifetime risk...
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