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Article

Genetic screening for hypertrophic cardiomyopathy in large, asymptomatic military cohorts.

American journal of medical genetics. Part C, Seminars in medical genetics - 1 Mar 2020

Brough Joe, Jain Mahim, Jerves Teodoro, Kruszka Paul, McGuffey Elizabeth

Abstract excerpt

Sudden cardiac death (SCD) is one of the leading causes of mortality in the U.S. military and competitive athletes. In this study, we simulate how genetic screening may be implemented in the military to prevent an SCD endpoint resulting from hypertrophic cardiomyopathy (HCM). We created a logistic regression model to predict variant pathogenicity in the most common HCM associated genes MYH7 and MYBPC3. Model...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32030882
DOI: 10.1002/ajmg.c.31772

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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