Article
Prediction of short-term neonatal complications in preterm infants using exome-wide genetic variation and gestational age: a pilot study.
Pediatric research - 1 Oct 2020
Stewart William C L, Gnona Komla M, White Peter, Kelly Ben, Klebanoff Mark, Buhimschi Irina A, Nelin Leif D
Abstract excerpt
BACKGROUND: Preterm birth is the leading cause of mortality and morbidity in young children, with over a million deaths per year worldwide arising from neonatal complications (NCs). NCs are moderately heritable although the genetic causes are largely unknown. Therefore, we investigated the impact of accumulated genetic variation (burden) on NCs in non-Hispanic White (NHW) and non-Hispanic Black (NHB) preterm...
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