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Article

Long Noncoding RNA HUPCOS Promotes Follicular Fluid Androgen Excess in PCOS Patients via Aromatase Inhibition

4 Feb 2020

Abstract excerpt

CONTEXT: Androgen excess is a key feature of polycystic ovary syndrome (PCOS), but the underlying molecular mechanism remains unclear. OBJECTIVE: To determine the role and mechanism of novel long noncoding RNA (lncRNA) highly up-regulated in PCOS (HUPCOS) in the androgen excess of PCOS patients. DESIGN: The lncRNA expression profile in granulosa cells derived from PCOS and non-PCOS women were analyzed by using...

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PMID: 32016412
DOI: 10.1210/clinem/dgaa060

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