Article
HER2 Gene Amplification in ER-positive HER2 Immunohistochemistry 0 or 1+ Breast Cancer With Early Recurrence.
Anticancer research - 1 Feb 2020
Yamashita Hiroko, Ishida Naoko, Hatanaka Yutaka, Hagio Kanako, Oshino Tomohiro, Takeshita Takashi, Kanno-Okada Hiromi, Shimizu A I, Hatanaka Kanako C, Matsuno Yoshihiro
Abstract excerpt
BACKGROUND/AIM: In estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer, standard chemotherapies as well as adjuvant endocrine therapy might not be enough for prevention of early relapse. MATERIALS AND METHODS: We focused on ER-positive, HER2 immunohistochemistry (IHC) 0 or 1+ breast cancer, and retrospectively examined HER2 gene amplification and TP53 mutation...
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