Women with fair phenotypes seem to confer a survival advantage in a low UV milieu. A nested matched case control study.

Abstract excerpt

BACKGROUND: Sun exposure in combination with skin pigmentation is the main determinant for vitamin D status. Human skin color seems to be adapted and optimized for regional sun ultraviolet (UV) intensity. However, we do not know if fair, UV-sensitive skin is a survival advantage in regions with low UV radiation. METHODS: A population-based nested case-control study of 29,518 Caucasian women, ages 25 to 64 years...

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