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The pro- and anti-cancer effects of oxycodone are associated with epithelial growth factor receptor level in cancer cells

22 Jan 2020

Abstract excerpt

BACKGROUND: Oxycodone is an opioid medication used for the treatment of pain in cancer patients. However, little is known on the direct effects of oxycodone on cancer cells. AIM: To determine the effects and mechanisms of oxycodone in cancer cells. MATERIALS AND METHODS: Proliferation, survival and migration assays were performed on multiple types of cancer cells. Epithelial growth factor receptor (EGFR)/ERK/Akt...

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PMID: 31967294
DOI: 10.1042/bsr20193524

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