The moderating effect of FKBP5 and 5-HTTLPR polymorphisms on the day-level association between drinking to cope motivation and negative affect.

doi:10.1016/j.psychres.2020.112756

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Article

The moderating effect of FKBP5 and 5-HTTLPR polymorphisms on the day-level association between drinking to cope motivation and negative affect.

Psychiatry research - 1 Feb 2020

Covault Jonathan, Armeli Stephen, Tennen Howard

Abstract excerpt

Daily levels of drinking to cope (DTC) have been found to be related to negative outcomes such as increased negative affect, and these effects vary across person. We examined whether daily-level effects of DTC motivation were related to two genetic polymorphisms (rs1360780 in the FKBP5 gene and 5-HTTLPR in SLC6A4) thought to be associated with maladaptive drinking and stress-reactivity. We also examined whether...

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Identifiers

PMID: 31931271
DOI: 10.1016/j.psychres.2020.112756
PMCID: PMC7017904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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