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Article

Crystal structure of an oxidized mutant of human mitochondrial branched-chain aminotransferase.

Acta crystallographica. Section F, Structural biology communications - 1 Jan 2020

Herbert Darius, Gibbs Synphane, Riddick Alexys, Conway Myra, Dong Ming

Abstract excerpt

This study presents the crystal structure of a thiol variant of the human mitochondrial branched-chain aminotransferase protein. Human branched-chain aminotransferase (hBCAT) catalyzes the transamination of the branched-chain amino acids leucine, valine and isoleucine and α-ketoglutarate to their respective α-keto acids and glutamate. hBCAT activity is regulated by a CXXC center located approximately 10 Å from...

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Identifiers

PMID: 31929181
DOI: 10.1107/S2053230X19016480
PMCID: PMC6957111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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