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Article

Vestibular function in severe GH deficiency due to an inactivating mutation in the GH-releasing hormone receptor gene.

Endocrine - 1 Mar 2020

Santos-Carvalho Hugo A, Aguiar-Oliveira Manuel H, Salvatori Roberto, Valença Eugênia H O, Andrade-Guimarães Alana L, Palanch-Repeke Carlos E, Moreira-Cândido Luan P, Araújo-Daniel Carlos R, de Oliveira-Barreto Aline C, Andrade Bruna M R, Oliveira Alaide H A, Vieira Edgar R, Gois-Junior Miburge B

Abstract excerpt

PURPOSE: Body balance involves the vestibular, visual, and proprioceptive systems. IGF-I is a GH-dependent key factor in the development and postnatal differentiation of the inner ear in mice and men, but its role in the vestibular function in adult humans is unknown. We have previously described a cohort of individuals with severe isolated GH deficiency (IGHD) caused by a mutation in the GHRH receptor (GHRHR)...

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PMID: 31902114
DOI: 10.1007/s12020-019-02178-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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