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Article

The application of big data to cardiovascular disease: paths to precision medicine.

The Journal of clinical investigation - 2 Jan 2020

Leopold Jane A, Maron Bradley A, Loscalzo Joseph

Abstract excerpt

Advanced phenotyping of cardiovascular diseases has evolved with the application of high-resolution omics screening to populations enrolled in large-scale observational and clinical trials. This strategy has revealed that considerable heterogeneity exists at the genotype, endophenotype, and clinical phenotype levels in cardiovascular diseases, a feature of the most common diseases that has not been elucidated by...

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PMID: 31895052
DOI: 10.1172/JCI129203
PMCID: PMC6934200

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