Article
Therapeutic effect of whole brain radiotherapy on advanced NSCLC between EGFR TKI-naïve and TKI-resistant.
Radiation oncology (London, England) - 31 Dec 2019
Zhao Lihao, Cai Xiaona, Chen Didi, Ye Xuxue, Gao Mengdan, Lu Lihuai, Su Huafang, Su Meng, Hou Meng, Xie Congying
Abstract excerpt
BACKGROUND: The development of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) has dramatically improved the prognosis of patients with EGFR-mutant non-small-cell lung cancer (NSCLC). The purpose of this study is to investigate the clinical outcome with or without EGFR-TKI resistance before WBRT and the sequence between EGFT-TKIs and whole brain radiotherapy (WBRT) of EGFR-mutant NSCLC...
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