Article
Predicting Amyloid-β Levels in Amnestic Mild Cognitive Impairment Using Machine Learning Techniques.
Journal of Alzheimer's disease : JAD - 1 Jan 2020
Ezzati Ali, Harvey Danielle J, Habeck Christian, Golzar Ashkan, Qureshi Irfan A, Zammit Andrea R, Hyun Jinshil, Truelove-Hill Monica, Hall Charles B, Davatzikos Christos, Lipton Richard B
Abstract excerpt
BACKGROUND: Amyloid-β positivity (Aβ+) based on PET imaging is part of the enrollment criteria for many of the clinical trials of Alzheimer's disease (AD), particularly in trials for amyloid-targeted therapy. Predicting Aβ positivity prior to PET imaging can decrease unnecessary patient burden and costs of running these trials. OBJECTIVE: The aim of this study was to evaluate the performance of a machine learning...
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