Article
The genetics of isolated congenital heart disease.
American journal of medical genetics. Part C, Seminars in medical genetics - 1 Mar 2020
Nees Shannon N, Chung Wendy K
Abstract excerpt
The genetic mechanisms underlying congenital heart disease (CHD) are complex and remain incompletely understood. The majority of patients with CHD have an isolated heart defect without other organ system involvement, but the genetic basis of isolated CHD has been even more difficult to elucidate compared to syndromic CHD. Our understanding of the genetics of isolated CHD is advancing in large part due to advances...
Topics
- Gene Regulatory Networks
- Genetic Predisposition to Disease
- Genetic Testing
- Heart Defects, Congenital
- High-Throughput Nucleotide Sequencing
- Humans