The X chromosome and male infertility.

Abstract excerpt

The X chromosome is a key player in germ cell development, as has been highlighted for males in previous studies revealing that the mammalian X chromosome is enriched in genes expressed in early spermatogenesis. In this review, we focus on the X chromosome's unique biology as associated with human male infertility. Male infertility is most commonly caused by spermatogenic defects to which X chromosome dosage is...

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• Share to Chromosomes, Human, X
• Share to Genes, X-Linked
• Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities