A high-grade glioma with SOS1 amplification.

doi:10.5414/NP301182

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Article

A high-grade glioma with SOS1 amplification.

Clinical neuropathology - 1 Jan 2000

Vidal Barbara, Bryke Christine, Hsu Nancy, Alterman Ronnie, Yeo Alan T, Charest Al, Varma Hemant

Abstract excerpt

The molecular alterations underlying progression of low-grade glial/glioneuronal tumors remain to be elucidated. We present a case of a 56-year-old male with an enhancing left temporal lobe tumor. Histology revealed a high-grade glioma adjacent to a low-grade glioneuronal component with abundant Rosenthal fibers, focal eosinophilic granular bodies, and CD34-positive neurons. The tumor was negative for IDH1...

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PMID: 31841105
DOI: 10.5414/NP301182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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