Article
Involvement of RUNX and BRD Family Members in Restriction Point.
Molecules and cells - 31 Dec 2019
Lee Jung-Won, Park Tae-Geun, Bae Suk-Chul
Abstract excerpt
A tumor is an abnormal mass of tissue that arises when cells divide more than they should or do not die when they should. The cellular decision regarding whether to undergo division or death is made at the restriction (R)-point. Consistent with this, an increasingly large body of evidence indicates that deregulation of the R-point decision-making machinery accompanies the formation of most tumors. Although the...
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