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Article

Pathophysiological connections between gallstone disease, insulin resistance, and obesity

8 Dec 2019

Abstract excerpt

Obesity and cholesterol gallstone disease (GSD) are frequently coexisting diseases; therefore and considering the current worldwide obesity epidemics, a precise understanding of the pathophysiological relationships between GSD and insulin resistance (IR) is important. Classically, obesity has been understood as a risk factor for GSD and the gallbladder (GB) viewed as a simple bile reservoir, with no metabolic...

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PMID: 31814283
DOI: 10.1111/obr.12983

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