Article
Three Children Treated with Direct-acting Antivirals for Chronic Hepatitis C Virus Genotype 1b Infection.
Internal medicine (Tokyo, Japan) - 1 Apr 2020
Ohya Kazuki, Kawaoka Tomokazu, Imamura Michio, Morio Kei, Nakahara Takashi, Murakami Eisuke, Yamauchi Masami, Hiramatsu Akira, Tsuge Masataka, Aikata Hiroshi, Chayama Kazuaki
Abstract excerpt
Although direct-acting antivirals (DAAs) have significantly increased the sustained virological response (SVR) rates in chronic hepatitis C virus (HCV)-infected adult patients, the efficacy and safety for children remain unclear. We herein report three HCV-infected children who received DAA treatment. The patients were girls 10-13 years old who had been infected with genotype 1b HCV by vertical transmission based...
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