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Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes

25 Nov 2019

Abstract excerpt

Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing islet β cells. Biomarkers capable of identifying T1D risk and dissecting disease-related heterogeneity represent an unmet clinical need. Toward the goal of informing T1D biomarker strategies, we profiled coding and noncoding RNAs in human islet-derived exosomes and identified RNAs that were differentially expressed...

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PMID: 31775218
DOI: 10.3390/ijms20235903

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