Article
Neural Transcription Correlates of Multimodal Cortical Phenotypes during Development.
Cerebral cortex (New York, N.Y. : 1991) - 14 May 2020
Pecheva Diliana, Lee Annie, Poh Joann S, Chong Yap-Seng, Shek Lynette P, Gluckman Peter D, Meaney Michael J, Fortier Marielle V, Qiu Anqi
Abstract excerpt
During development, cellular events such as cell proliferation, migration, and synaptogenesis determine the structural organization of the brain. These processes are driven in part by spatiotemporally regulated gene expression. We investigated how the genetic signatures of specific neural cell types shape cortical organization of the human brain throughout infancy and childhood. Using a transcriptional atlas and...
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