Article
Designing a QTL Mapping Study for Implementation in the Realized Collaborative Cross Genetic Reference Population.
Current protocols in mouse biology - 1 Dec 2019
Soller Morris, Abu-Toamih Atamni Hanifa J, Binenbaum Ilona, Chatziioannou Aristotelis, Iraqi Fuad A
Abstract excerpt
The Collaborative Cross (CC) mouse resource is a next-generation mouse genetic reference population (GRP) designed for high-resolution mapping of quantitative trait loci (QTL) of large effect affecting complex traits during health and disease. The CC resource consists of a set of 72 recombinant inbred lines (RILs) generated by reciprocal crossing of five classical and three wild-derived mouse founder strains....
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