Common polymorphic inversions at 17q21.31 and 8p23.1 associate with cancer prognosis.

doi:10.1186/s40246-019-0242-2

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Article

Common polymorphic inversions at 17q21.31 and 8p23.1 associate with cancer prognosis.

Human genomics - 21 Nov 2019

Ruiz-Arenas Carlos, Cáceres Alejandro, Moreno Victor, González Juan R

Abstract excerpt

BACKGROUND: Chromosomal inversions are structural genetic variants where a chromosome segment changes its orientation. While sporadic de novo inversions are known genetic risk factors for cancer susceptibility, it is unknown if common polymorphic inversions are also associated with the prognosis of common tumors, as they have been linked to other complex diseases. We studied the association of two...

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Identifiers

PMID: 31753042
DOI: 10.1186/s40246-019-0242-2
PMCID: PMC6873427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.