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Article

Verification of hub genes in the expression profile of aortic dissection.

PloS one - 1 Jan 2019

Wang Weitie, Liu Qing, Wang Yong, Piao Hulin, Li Bo, Zhu Zhicheng, Li Dan, Wang Tiance, Xu Rihao, Liu Kexiang

Abstract excerpt

BACKGROUND: To assess the mRNA expression profile and explore the hub mRNAs and potential molecular mechanisms in the pathogenesis of human thoracic aortic dissection (TAD). METHODOLOGY: mRNA microarray expression signatures of TAD tissues (n = 6) and non-TAD tissues (NT; n = 6) were analyzed by an Arraystar human mRNA microarray. Real-time PCR (qRT-PCR) was used to validate the results of the mRNA microarray....

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PMID: 31751374
DOI: 10.1371/journal.pone.0224922
PMCID: PMC6872142

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