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Article

Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas.

Medicinal research reviews - 1 May 2020

Khan Tuhina, Relitti Nicola, Brindisi Margherita, Magnano Stefania, Zisterer Daniela, Gemma Sandra, Butini Stefania, Campiani Giuseppe

Abstract excerpt

Oral squamous cell carcinomas (OSCC) and esophageal squamous cell carcinomas (ESCC) exhibit a survival rate of less than 60% and 40%, respectively. Late-stage diagnosis and lack of effective treatment strategies make both OSCC and ESCC a significant health burden. Autophagy, a lysosome-dependent catabolic process, involves the degradation of intracellular components to maintain cell homeostasis. Targeting...

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PMID: 31742748
DOI: 10.1002/med.21646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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