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Chronic obstructive pulmonary disease (COPD) and lung cancer: common pathways for pathogenesis

1 Oct 2019

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) and lung cancer comprise the leading causes of lung disease-related mortality worldwide. Exposure to tobacco smoke is a mutual aetiology underlying the two diseases, accounting for almost 90% of cases. There is accumulating evidence supporting the role of immune dysfunction, the lung microbiome, extracellular vesicles and underlying genetic susceptibility in the...

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PMID: 31737343
DOI: 10.21037/jtd.2019.10.54

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